Hemostatic changes in patients with chronic renal failure

  • Harith Y. Serrheed Medical city (Baghdad), international center of teaching lab.
  • Eman J. Mohammed Medical city, Baghdad hospital
Keywords: chronic renal failure, prothrombin time, Thrombin time, bleeding time, activated partial thromboplastin time.


Background: Renal disease results in significant disorder of hemostasis (bleeding diathesis or
hypercoagulable state).
Objectives: This study is to determine the changes in some hemostasis parameters in patients with
chronic renal failure and identify the effect of dialysis on these changes.
Patients and Methods: seventy five patients with end stage chronic renal failure were collected from
Baghdad hospital, a full detailed history and clinical examination were performed, 50 patients were on
maintenance weekly hemodialysis, and 25 patients were without dialysis.
Result: Bleeding time was significantly higher in patients with chronic renal failure who didn’t need
any type of dialysis, positive D-Dimer test. In some patients, Platelet count, prothrombin time, thrombin
time, fibrinogene level, activated partial thromboplastin time; all did not reach significant level between
both groups of patients.
Conclusion: hemostatic changes are not uncommon in patients with chronic renal failure, affecting the
different parameter hemostasis so it should be consider in the management of these patients.


Download data is not yet available.
How to Cite
Serrheed H, Mohammed E. Hemostatic changes in patients with chronic renal failure. JFacMedBagdad [Internet]. 2Sep.2018 [cited 9May2021];60(2):85-8. Available from: https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/10