https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/issue/feed Journal of the Faculty of Medicine Baghdad 2022-04-24T23:40:48+00:00 prof. Mohammed M. Al-Anni Misk62@yahoo.com Open Journal Systems <h3>Journal of the Faculty of Medicine – University of Baghdad</h3> <h3>A peer-reviewed journal published Quarterly by the college of medicine –Baghdad University</h3> <h3>ISSN:&nbsp; &nbsp;0041-9419</h3> <h3>E-ISSN: 2410-8057</h3> <h3>The Journal interested in the publication of clinical and basic medical research.</h3> <h3>The first issue of this Journal was published under the name of (Journal of the Royal Iraqi Medical College) in April /1936, approved by the council of the College as a general journal dealing with the news of the college and few scientific articles to encourage the teaching staff for research publication. The journal was published randomly and ceased during World War II due to financial difficulties.</h3> <h3>In 1946 Prof. Dr. Hashim Al Witri, the college dean, assigned republication of the journal and urged the teaching staff to participate and publish their research in the journal. Despite his effort, the journal remained irregular in publication. In 1959&nbsp; Prof. Dr. Faisal Al-Sabih became the Editor in Chief of the journal when he returned from the United Kingdom and appointed on the teaching staff, restructured the journal and changed its name to (The Journal of the Faculty of Medicine) and used a new scientific system for publication of articles.</h3> <h3>The first issue of the new series started in June 1959. The journal continued to be published on a regular basis since then without interruption in (four issues during the year). The journal became registered the international number (ISSN) in 2000 and entered in many important international indexes.</h3> <h3>After 2003 the journal continued despite the difficulties involved in every aspect of the country and by the beginning of 2004, the journal progressed through a series of changes to reach a level that can be recognized internationally.</h3> <h3>After 2010 the journal became published electronically of the same edited issues.</h3> https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1881 Cephalosporins are the not the cause of death in a pregnant with urinary tract infection; A case Report 2022-02-28T06:41:21+00:00 Mohammed Abdul- Hassan Jabarah mjabarah.17@gmail.com <p><strong>Background</strong>: Urinary tract infection is a highly prevalent disease all over the world and affects females more than males. In the former, it may complicate pregnancy to potentially lethal septicaemia. Therefore, the aim of current case report was to show how misinterpretation of symptoms of septicaemia can lead to inadequate, and probably inappropriate, management with subsequent medico-legal consequences. <strong>Methods</strong>: A case study of a young pregnant female who developed urinary tract infection and treated with parenteral cephalosporins. The infection developed into septicaemia with subsequent miscarriage and death of the patient. <strong>Discussion: </strong>Misinterpretation of the symptoms of septicaemia resulted into delayed and inadequate management of the patient that resulted in death of the fetus, loss of consciousness of the patient and her death after that. <strong>Conclusion</strong>: Urinary tract infection during pregnancy may progress to septicaemia. Therefore, an early diagnosis and effective treatment may reduce potentially fatal outcomes.</p> <p>&nbsp;</p> <p>&nbsp;</p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 Mohammed Abdul- Hassan Jabarah https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1884 The outcome of Pleurodesis in Malignant Pleural Effusion 2022-01-30T06:46:12+00:00 waleed M. hussen dr_waleedmustafa@yahoo.com Ali H. Said Alialaqabe10@gmail.com Osama Elhassani dralhassani@yahoo.com <p><strong><u>Background:</u></strong> Accumulation of fluid in pleural space, which is malignant in nature, is secondary to lung, breast or ovarian tumors. Metastatic Adeno Ca is most commonly seen in male and breast Ca is most commonly seen in female. It indicates advanced disease and reduced survival.</p> <p><strong><u>Aim:</u></strong> Is to study prospectively thirty patients with malignant pleural effusion according to their clinical presentation, ways of diagnosis, and methods of chemical pleurodesis.</p> <p><strong><u>Patient and methods</u>:</strong> Data of thirty patients with malignant pleural effusion collected and analyzed using a form to categorize them according to their age, gender, presenting features, imaging studies and procedure performed to drain the fluid and to arrange chemical pleurodesis.</p> <p><strong><u>Results:</u></strong> Eighteen patients were male; twelve patients were female in a ratio of 1.5:1. The youngest was 52 years old while the oldest was 81 years old. The mean age was 65.8 ±7.34. The most frequent presenting features were cough and dyspnea. Imaging studies showed that eleven patients had left sided effusion with underlying mass. Eight patients had right sided effusion with underlying mass while the remaining eleven patients had only effusion. Twenty patients received (Talc) and ten patients received (Bleomycin) with comparable recurrence rate of the effusion, in seven patients out of 20 in Talc (35%) and in three out of 10 patients received Bleomycin (30%).</p> <p><strong><u>Conclusion:</u></strong> Malignant pleural effusion should be drained nearly complete evacuation; regardless the primary cause, prior to installation of agent for pleurodesis and both (Talc &amp; Bleomycin) can be used with comparable results and recurrence</p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 waleed M. hussen, Ali H. Said, Osama Elhassani https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1886 A Congenital anomalies and early neonatal mortality: A tertiary hospital study. 2022-02-07T07:37:21+00:00 Hossam S. Talab dhossamsubhi79@gmail.com Ahmed Kamal paedopaedo13@gmail.com Khalid Z. Naama Khalid.zuheir@yahoo.com <p><strong>Background</strong>: The prevalence of congenital anomalies at birth is underestimated in developing countries due to the unavailability of perinatal diagnostic tests or accurate medical records. &nbsp;The prevalence of congenital defects may help to establish a baseline, track changes over time, and uncover etiological clues.</p> <p><strong>Objectives:</strong> This study aims to evaluate the prevalence and types of major congenital anomalies in one of the main referral tertiary centers in Baghdad, highlighting the parent and neonatal characteristics and assessing the mortality rate in this group of patients.</p> <p><strong>Patients and Methods:</strong> A prospective cohort study was conducted in Baghdad Teaching Hospital during the period between May 2017 and May 2018. Total deliveries were 6553, all live neonates with congenital anomalies were included regardless of their gestational age or birth weight. The patient's hospital notes were reviewed for the patient's characteristics, parentage, maternal chronic disease, and drug history, and other study parameters. The early neonatal outcome was assessed within 7 days of the delivery.</p> <p><strong>Results:</strong> The prevalence of congenital malformations was 21.5 per 1000 birth with the highest frequent anomaly affecting the nervous system (41.1%) followed by multiple syndromic malformations (12.8%) and digestive system (11.3%). The mean maternal age was 27.8 (±7.8) ranging from 14-47. The rate of diseased mothers was 18.4%, only half of them were on regular medications. Out of a total of 399 early neonatal death during the study period, death due to congenital malformations constituted 19.8%.&nbsp; Congenitally deformed patients died at a rate of 56%, which was significantly associated with gestational age and neonatal birth weight.</p> <p><strong>Conclusion:</strong> The prevalence of congenital abnormalities has increased in the same hospital over the last decade. Mortality rate of these patients is high and associated with gestational age and birth weight. It is critical to test for congenital malformations early in pregnancy, particularly for high-risk parents with advanced age, consanguinity, and history of congenital anomalies.</p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 Hossam S. Talab , Ahmed Kamal, Khalid Z. Naama https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1866 Duplex ultrasound surveillance for asymptomatic deep venous thrombosis after total knee joint replacement 2021-12-13T09:31:59+00:00 Arwa Mohsun Khalil dr.arwamohsun@yahoo.com Safwan Saeed Mohammed dr.safwansaeed@gmail.com <p><strong>Background:</strong> The prevalence of deep veins thrombosis, complicating total knee replacement in Asian countries, has not been fully appreciated in comparison to western countries as there are few studies on that. There is an important correlation between the evidence of deep veins thrombosis in the lower extremity and likelihood of pulmonary embolism later one . Because of its noninvasive nature, duplex ultrasound has become one of the initial dependable modality for the cheek out of deep veins thrombosis after total knee replacement . Therefore, this study was designed to evaluate the outcome of asymptomatic after total knee replacement by duplex ultrasound among Iraqi patients.</p> <p><strong>Methods: </strong>This prospective study was conducted at AL-Shaheed Gazi AL-Hariri specialized Surgical Hospital, Radiology department, Ultrasound unit form from October 2009 to October 2010. Duplex ultrasound surveillance for asymptomatic deep venous thrombosis was done on 30 patients (13 females and 17 males ) who had underwent total knee replacement at day 5-7 postoperatively to investigate the evidence of deep venous thrombosis after total knee joint replacement among Iraqi patients.</p> <p><strong>Results: </strong>The percentage of deep veins thrombosis in this study was found to be 23.33%. Of these, 14% occurred in the popliteal and 86% occurred in the calf vein. Patients’ gender was not associated with significant higher incidence of deep veins thrombosis .Although the incidence of deep veins thrombosis in patients aged more than 50 years was higher than in patients aged 30-50 years, it did not reach a statistically significant level. There was statistically significant relationship between obesity and the development of deep veins thrombosis. Patients with sedentary lifestyle showed higher incidence of deep veins thrombosis than patients with non-sedentary lifestyle and the difference reached a statistically significant level. The duration of the operation showed a significant correlation with the incidence of deep veins thrombosis when the operation lasted more than 2 hours. In addition, there was higher incidence of deep veins thrombosis among smokers compered to non-smokers.</p> <p><strong>Conclusion: </strong>The evidence of deep veins thrombosis was 22.33% in spite of anticoagulation coverage. Also, duplex ultrasonography is suggested after total knee replacement, especially in patients who have other risk factors.</p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 Arwa Mohsun Khalil, Safwan Saeed Mohammed https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1887 Prevalence of Lung Cancer in Al Najaf Governorate Registered in Middle Euphrates Oncology Center during 2019 and 2020 2022-02-13T07:42:08+00:00 Zahraa Al-Khateeb Zahraa.alkhateeb90@gmail.com Liwaa Mahdi Liwaa.alkulabi@uokufa.edu.iq <p><strong>Background: </strong>Lung cancer is a disease in which cells in the lung grow out of control and may spread to lymph nodes or other organs in the body such as the brain. Cancer from other organs also may spread to the lungs. The chance that a man will develop lung cancer in his lifetime is about 1 in 15; for a woman, the risk is about 1 in 17. These numbers include both people who smoke and those who don't smoke. Worldwide; prevalence of the lung cancer was decreased in the last decade.</p> <p><strong>Objectives: </strong>To determine the prevalence of lung cancer in Al Nagaf Governorate during 2019 and 2020</p> <p><strong>Patients</strong> <strong>and Methods:</strong></p> <p>A Registry-based cross sectional study was conducted at middle Euphrates oncology center in Al Najaf city from October 2021 to February 2022. data was collected from this center and from the Iraqi National Cancer Registry (INCR) annual reports. Independent t test (Mean±SD) and <em>X<sup>2</sup></em> test was used,&nbsp;P value at &lt; 0.05 was significant. <strong>Results: </strong>In 2019; there were 98 (53.60%) patients diagnosed with lung CA, while in 2020, there were 85 (46.40%) patients. 59 (32.20%) patients were within age 60-69 years and 59 (32.20%) patients were within age 70-79 years. There were 125 (68.3%) males and 58 (31.7%) females, 138 (75.40%) smokers, and 59 (32.20%) patients were overweight. 103 (56.3%) patients diagnosed with SCC, 43 (23.5%) with adenocarcinoma, 32 (17.5%) with small cell CA. Cancer metastasis found among 108 (59%) patients. bone in 35 (19.1%) patients and to the Liver in 30 (16.4%) patients. Prevalence of Lung CA in 2019 was 6.5/10<sup>5 </sup>(in males 8.72/10<sup>5 </sup>and 4.25/10<sup>5 </sup>in females). During 2020; there were 59 males and 26 females. Prevalence of Lung CA was 5.5/10<sup>5</sup> (in males 6.7/10<sup>5 </sup>and 3.4/10<sup>5 </sup>in females). Small cell CA was significantly associated with patients aged 60-69 years, smokers, diagnosis with biopsy, metastasis to the supraclavicular LN, and metastasis to the liver (P&lt;0.05).</p> <p><strong>Conclusions: </strong>Prevalence of lung CA in 2019 was higher than that in 2020. Males were dominant in lung CA. Metastasis was found among more than half of patients; bone and liver were the most common metastasized organs. The most common types of cancer were Squamous Cell CA, adenocarcinoma, and Small Cell CA.</p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 Zahraa Al-Khateeb, Liwaa Mahdi; rabh angel https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1896 THE CLINICAL PROFILE AND CORONARY ARETERY FINDINGS IN PATIENTS WITH ATRIAL FIBRILLATION 2022-04-10T09:02:07+00:00 Saleh Ali Saleh saleh76@gmail.com Faris kadhim Khadir Faris.bermani@al-yarmok.edu.iq Ameen Al- Alwany ameen.a@comed.uobaghdad.edu.iq <p><strong>Background:</strong> Atrial fibrillation (AF) is a common arrhythmia in daily practice and one of the heart disorders with the highest morbidity and death rates, as it is responsible for a huge number of negative consequences. In our country, there is limited information on the prevalence or natural history of the less well-defined clinical types.</p> <p><strong>Objective:</strong> to evaluate the clinical profile and coronary artery findings in atrial fibrillation patients.</p> <p><strong>Patients and Methods: </strong>This cross-sectional study was conducted during the period from the first of October 2019 to end of July 2021 at the Iraqi Center for the heart disease at Baghdad Medical City. Included 32 Iraqi patients with atrial fibrillation of both genders. Angiography performed through the femoral Artery approach, Data collected by history, through clinical examination and investigations, using data collection sheet</p> <p><strong>Results: </strong>The main type of AF was chronic, (62.5%), Echocardiography findings revealed Systolic dysfunction in 31.1% of patients, Diastolic dysfunction in 37.5%, and both dysfunctions in 6.2%, Left atrium was dilated in 13 (40.6%). Angiographic findings revealed RCA lesion in 13 (40.6%) patients, LCA in 9 (28.1%) while both RCA and LCA lesions present in 3 (9.4%) patients. LAD lesions reported in 10 (31.2%) patients, LCX in 27.8% and LMS in 16.8%.</p> <p><strong>Conclusion</strong>: Chronic AF was the more frequent type, Systolic and diastolic dysfunction are frequent among AF patients. RCA was more frequently affected than LCA, LAD was the more affected branch.</p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 Dr. Saleh Ali Saleh, Dr.Faris kadhim Khadir, Ameen Al- Alwany https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1871 use of dietary supplement in Iraq 2022-01-17T09:10:53+00:00 Sami S. Shihab ssshihab2@gmail.com Haidar M. Jawad haidarm.jawad@comed.uobaghdad.edu.iq zahraa matheel nasir zahraamathel@gmail.com Eman M. Jasim Pharmacist.eman2018@gmail.com <p><strong>Background</strong>: Dietary supplementation is a common strategy to achieve a specific health status or performance benefit. The aim of this study was to describe the use of dietary supplement in Iraqi genders.</p> <p><strong>Patients and </strong><strong>Methods</strong>: several questions on dietary supplement use were asked as a part of single performed on 112 female and 247 women aged 35–74 years in 2021 .n = 359) ,reported the frequency and prevalence of supplement use by sex and type of supplement .</p> <p><strong>Results:</strong> the mean percentage of dietary supplement use varied among female and men. Use was higher in women than in men. Vitamins, minerals were the predominant types of supplements reported, but there were striking differences between genders. Vitamins, particularly D, C, were the most frequently used ingredients by both genders. Herbals use in female more than male.</p> <p><strong>Conclusions</strong>: This study indicates that there are wide variations in supplement use in Iraq, which may affect individual and population nutrient intakes. The results underline the need to monitor consumption of dietary supplements, as well as to evaluate the risks and benefits.</p> <p><strong>Keywords</strong>:</p> <p><strong>Abstract </strong></p> <p><strong>Background</strong>: Dietary supplementation is a common strategy to achieve a specific health status or performance benefit. The aim of this study was to describe the use of dietary supplement in Iraqi genders.</p> <p><strong>Patients and </strong><strong>Methods</strong>: several questions on dietary supplement use were asked as a part of single performed on 112 female and 247 women aged 35–74 years in 2021 .n = 359) ,reported the frequency and prevalence of supplement use by sex and type of supplement .</p> <p><strong>Results:</strong> the mean percentage of dietary supplement use varied among female and men. Use was higher in women than in men. Vitamins, minerals were the predominant types of supplements reported, but there were striking differences between genders. Vitamins, particularly D, C, were the most frequently used ingredients by both genders. Herbals use in female more than male.</p> <p><strong>Conclusions</strong>: This study indicates that there are wide variations in supplement use in Iraq, which may affect individual and population nutrient intakes. The results underline the need to monitor consumption of dietary supplements, as well as to evaluate the risks and benefits.</p> <p><strong>Keywords</strong>: Dietary supplements type; Iraq; vitamins; minerals, herbals.</p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 Sami S. Shihab, Haidar M. Jawad, zahraa matheel nasir, Eman M. Jasim https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1888 Detection of BRAFV600E Biomarker In Patients With Colorectal Cancer Using Immunohistochemical Techniques / Clinico-Pathological Study 2022-04-03T08:10:24+00:00 Seror Abdul Kareem Turkan Alrubaiaee soso.ok.89@gmail.com Thaeer Jawad Kadhim Al-taee alihala.ah.88@gmail.com <p><strong>Background</strong><strong> :</strong></p> <p>Colorectal cancer (CRC) is the 4<sup>th</sup> common gastrointestinal cancer. (BRAF<strong><sup>V600E</sup></strong>) is a member of RAF family of serine/threonine protein kinases that function to regulate the (MAPK) / (ERK) pathway. BRAF<strong><sup>V600E</sup></strong> mutated CRC are associated with right-sided primary tumors, older women and high-grade tumors.</p> <p>Aims of the study:</p> <p>Study the immunohistochemical expression of <strong>BRAF<sup>V600E</sup></strong> biomarker in a sample of Iraqi patients with colorectal cancer and the correlation of<strong> BRAF<sup>V600E</sup></strong> expression with other clinicopathological variables such as patient's age and tumor grade.</p> <p><strong> </strong></p> <p><strong>Materials and Methods :</strong></p> <p>in this prospective study a total of 90 colorectal cases of a sample of Iraqi patients were collected from teaching labs of AL-Yarmouk Teaching Hospital including 60 cases of colorectal carcinoma and 30 cases of colorectal adenoma.</p> <p><strong> </strong></p> <p><strong>Result: </strong>BRAF<sup>V600E</sup> biomarker was positive in 16.6% of colorectal carcinoma group and negative in colorectal adenoma group.</p> <p><strong> </strong></p> <p><strong>Conclusions:</strong></p> <p>BRAF expression was higher in older patients ages &amp; higher tumor stages and there is no expression of BRAF<sup>V600E</sup> in adenoma cases.</p> <p><strong> </strong></p> <p> </p> 2022-04-24T00:00:00+00:00 Copyright (c) 2022 Dr.seror Alrubaiaee, Dr. Thaeer Al-taee