Thyroid Disorders and the Level of Malondialdehyde
DOI:
https://doi.org/10.32007/jfacmedbagdad.5111179الكلمات المفتاحية:
Thyroid Disorders,malondialdehyde.الملخص
Background: Free radicals have been implicated in many pathological processes, including ischemia, inflammation, and malignancy. The free radicals may affect tissues damage by lipid
peroxidation which generate malondialdehyde (MDA) as a by byproduct of the reaction. The objective of this study is to examine the dynamics of lipid peroxidation in patients with
thyroid disorders using the measurement of malondialdehyde level as a marker for the degree of thyroid disorder.
Methods: Two hundred and forty five subjects were enrolled in this study. Hundred and ninety five were patients with different thyroid disorders (88 yperthyroidism, 63 hypothyroidism and 44 thyroid carcinoma) the remaining 50 subjects were healthy ones without any apparent functional disorders served as a control. Malondialdehyde (MDA) level was estimated in the sera of all subjects.
Results: A significant increase in the level of serum MDA concentration was observed in patients with all types of thyroid disorders as compared with the control groups.
Conclusion: The findings obtained showed a high rate of lipid peroxidation.
التنزيلات
التنزيلات
منشور
إصدار
القسم
الرخصة
Permit others to copy and distribute the manuscript; to extract, revise, and create another derivative
works of or from the manuscript (e.g., a translation); to incorporate the manuscript into a
collective work; and to text or data mine the article, even for commercial purposes, provided that
the author(s) is/are credited; the article's modifications should not harm the author's honor or
reputation; and the article should not be altered in a way that would cause the author to lose them
reputation. The Creative Commons Attribution 4.0 International License (CC BY 4.0) has more
information.