Hemostatic changes in patients with chronic renal failure

  • Harith Y. Serrheed Medical city (Baghdad), international center of teaching lab.
  • Eman J. Mohammed Medical city, Baghdad hospital
Keywords: chronic renal failure, prothrombin time, Thrombin time, bleeding time, activated partial thromboplastin time.

Abstract

Background: Renal disease results in significant disorder of hemostasis (bleeding diathesis or
hypercoagulable state).
Objectives: This study is to determine the changes in some hemostasis parameters in patients with
chronic renal failure and identify the effect of dialysis on these changes.
Patients and Methods: seventy five patients with end stage chronic renal failure were collected from
Baghdad hospital, a full detailed history and clinical examination were performed, 50 patients were on
maintenance weekly hemodialysis, and 25 patients were without dialysis.
Result: Bleeding time was significantly higher in patients with chronic renal failure who didn’t need
any type of dialysis, positive D-Dimer test. In some patients, Platelet count, prothrombin time, thrombin
time, fibrinogene level, activated partial thromboplastin time; all did not reach significant level between
both groups of patients.
Conclusion: hemostatic changes are not uncommon in patients with chronic renal failure, affecting the
different parameter hemostasis so it should be consider in the management of these patients.

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Published
2018-09-02
How to Cite
1.
Serrheed H, Mohammed E. Hemostatic changes in patients with chronic renal failure. J Fac Med Bagdad [Internet]. 2Sep.2018 [cited 24Jan.2020];60(2):85-8. Available from: http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/10