Antagonstic Effect of Lactobacillus Fermentum Supernatant AgainstEnterococcus Faeciumand Enterococcus Faecalis In Vitro

Authors

  • Likaa H. Mahdi Dept. of Biology - College of Science –Al Mustansiriyah University
  • Sanaa N. Husain Dept. of Biology - College of Science –Al Mustansiriyah University

DOI:

https://doi.org/10.32007/jfacmedbagdad.542747

Keywords:

Lactobacillus fermentum , Antibacterial activity , Antagonstic effect ,Enterococcus faecium , Enterococcus faecalis, vaginosis .

Abstract

Background:Lactobacillus fermentum selected as an alternative treatment to prevent or treat urogenital infection based on their probiotics properties and production of bacteriocins.
Objective: The present work was done to study the inhibition activity of L. fermentum cell free supernatant against urogenital pathogens Enterococcus faecium and Enterococcus faecalisinvitro.
Materials and methods: L.fermentum isolates have been collected from vaginal swabs . A supernatant of these isolates has been prepared and its antibacterial activity against 3 isolates of E.faecium and 3 isolates of E.faecalis has been studied.
Results: Different concentrations have been prepared and the most effective one was 1000μg/ml and the most affected isolate of E.faecalis was no. 3 which its MIC was 64μg/ml and MBC was 128 μg/ml, while the most affected isolate of E. faecium was no. 1 which its MIC was 128 μg/ml and MBC was 256 μg/ml .
Conclusion:L. fermentumCFS showed significant activity against both Enterococcus isolates and showed closely related results.

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Published

2012-07-01

How to Cite

1.
Antagonstic Effect of Lactobacillus Fermentum Supernatant AgainstEnterococcus Faeciumand Enterococcus Faecalis In Vitro. JFacMedBagdad [Internet]. 2012 Jul. 1 [cited 2024 Mar. 28];54(2):154-7. Available from: https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/747

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