Correlation between Cognition and Quantitative EEG Changes in Patients with Migraine
DOI:
https://doi.org/10.32007/jfacmedbagdad.2151Keywords:
migraine, cognition, Electroencephalography, Spectral power densityAbstract
Background: Migraine is a common debilitating disorder characterized by attacks of mostly unilateral, moderate to severe, throbbingheadaches. The diagnosis of migraine is made according to the third edition of the International Classification of Headache Disorders developed by the International Headache Society. There are several types of migraine, the most common of which are migraine without aura and migraine with aura.
Objectives: This study aims to find the correlations between quantitative EEG changes and cognition in migraine patients.
Patients and Methods: The study included 20 migraine patients,10 during pain attack (ictal phase) and 10 during pain-free period (inter-ictal), in addition to18 healthy controls.Montreal cognitive assessment and 20 minutes scalp EEG were done. After that, four seconds epochs were taken from the EEG record to find the powerspectral density (PSD) for each of the waves in the range of[detlaδ(0.5-4)Hz, theta θ(4-8)Hz, alpha α (8-12)Hz,and beta β (12-30)Hz]. The study was conducted in Al-Shaheed Ghazi Al-Hariri Hospital in Baghdad from October 1, 2022, to May 1, 2023.
Results: Quantitative EEG analysis revealed that there is a significant decrease in theta and beta waves in descending pattern from control to inter-ictal and then to ictal migraine patientswhile alpha wave increased in ascending pattern from control to inter-ictal to ictal migraine patients. In cognition, there was a significant difference between controls and migraine patients in recall memory, language, and abstraction domains.
Conclusions: Quantitative EEG findings suggest that alpha waves correlate negatively with cognition, while both theta and beta waves correlate positively with cognitive level.
Received: June,, 2022
Accepted: Oct. 2023
Published: Jan.2024
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References
- Brennan KC, Pietrobon D (2018).A system neuroscience approach to migraine.neuron 97:1004-1021. https://doi.org/10.1016/j.neuron.2018.01.029
-AlGawwam G.(2015). Relationship between sex hormones and migraine. JFacMedBagdad 57(1):31-4. https://doi.org/10.32007/jfacmedbagdad.571303
-Durham PL, Vause CV (2010).Calcitoningene-related peptide (CGRP) receptor antagonist in the treatment of migraine. CNS Drugs. 24(7):539-548. https://doi.org/10.2165/11534920-000000000-00000
-Headache Classification Committee of the International Headache Society (his)(2018). The international classification of headache disorder,3rd edition, Cephalgia(1):1-211.
https://doi.org/10.1177/0333102417738202
-Stedman TL(2012).Stedman's medical dictionary for the health professions and nursing.Wolters Kluwer Health /Lippincott Williams and Wilkins, Philadelphia.
-Livingston G, Sommerland A, Orgeta V, Costafreda SG,Huntley J, Ames D,et al(2020).Dementia prevention, intervention, and care.Lancet 390:2673-2734https://doi.org/10.1016/S0140-6736(20)30367-6
-Zhou D,Meng R,Li SJ,Ya JY, Shang SL,Ding JY, et al(2018).Advances in chronic cerebral circulation insufficiency.CNS Neurosci Ther.24:5-17. https://doi.org/10.1111/cns.12780
-Zhuang L, Yang Y, and Gao J (2021).Cognitive assessment tools for mild cognitive impairment screening. J Neurol 268:1615-1622. https://doi.org/10.1007/s00415-019-09506-7
-Krishnan S,JustusS,Meluveettil R,Menon RN,Sarma SP,Kishore A (2015). Validity of Montreal Cognitive assessment in non-English speaking patients with Parkinson's disease. NeurolIndia;63:63-70. https://doi.org/10.4103/0028-3886.152637
-Mohammed SJ, Al-Madfai Z, Al-OwathMMH.(2012) Treatment Of Subclinical Epileptic Discharges Affects Cognitive Functions In Epileptic Patients. JFacMedBagdad54(1):42-6.
https://doi.org/10.32007/jfacmedbagdad.541769
-Thakor NV,and Tong S.(2004).Advances in quantitative electroencephalogram analysis method. Annual review of Biomedical Engineering,(6):453-495.
https://doi.org/10.1146/annurev.bioeng.5.040202.121601
-Nasreddine , Z. S. (n.d.). The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. MoCACognition. https://mocacognition.com/paper/
-Vellieux G, Amiel H, Roos C, Crassard I, Houdart E, Kubis N(2021). Spectral analysis of EEG in the etiological assessment of patients with transient neurological deficits. Neurophysiol. Clin. 51, 225-232. https://doi.org/10.1016/j.neucli.2021.04.001
-Clemens B, Bank J, Piros P, Bessenyei M, Veto S, Toth M. et al. (2008). Three-dimensional localization of abnormal EEG activity in migraine: A low-resolution electromagnetic tomography (loreta) study of migraine patients in the pain-free interval. Brain Topogr. 21, 36-42. https://doi.org/10.1007/s10548-008-0061-6
-Bjork MH, StovnerLJ, Engstrom M, Stjern M, Hagen K, and Sand T. (2009a). Interictal quantitative EEG in migraine: A blinded controlled study. J. Headache Pain 10, 331-339. https://doi.org/10.1007/s10194-009-0140-4
-Quadros MA, Granadeiro M, Ruiz-Tagle A, Maruta C, Gil-Gouveia R, Martins IP.(2020). Cognitive performance along the migraine cycle: A negative exploratory study. Cephalalgia3. https://doi.org/10.1177/2515816320951136
-Santangelo G, Russo A, Trojano L. (2016). Cognitive dysfunctions and psychological symptoms in migraine without aura: a cross-sectional study. J Headache Pain.;17:76. https://doi.org/10.1186/s10194-016-0667-0
-Wen K, Nguyen NT, Hofman A, Ikram MA, Franco OH.(2016). Migraine is associated with better cognition in the middle-aged and elderly: the Rotterdam Study. Eur J Neurol. 23(10):1510-6. https://doi.org/10.1111/ene.13066
-Rist PM, Kang JH, Buring JE, Glymour MM, Grodstein F, Kurth T.(2012). Migraine and cognitive decline among women: prospective cohort study BMJ, 345:e5027. doi: https://doi.org/10.1136/bmj.e5027
-Lithfous S, Tromp D, Dufour A, Pebayle T, Goutagny R, Després O. (2015).Decreased theta power at encoding and cognitive mapping deficits in elderly individuals during a spatial memory task. Neurobiol Aging.36(10):2821-9. https://doi.org/10.1016/j.neurobiolaging.2015.07.007
- Wang J,Xu J, Liu S,Han F, Wang Q,Gui H,et al(2021). Electroencephalographic Activity and Cognitive Function in Middle-Aged Patients with Obstructive Sleep Apnea Before and After Continuous Positive Airway Pressure Treatment.J. Nature and Science of sleep. 13:1495-1506. https://doi.org/10.2147/NSS.S322426
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