Immunofluorescen Study of Trophoblastic Bound Immunolglobuline G in preeclamptic women at term

Wifaq M. AL-Watar; khalida M. Al- Mousawy; wafa R. AL-Omari; warkaa mahmood ali

doi:10.32007/jfacmedbagdad.4721650

Authors

Wifaq M. AL-Watar Department of microbiology, college of medicine, Baghdad university, Iraq.
khalida M. Al- Mousawy Department of microbiology, college of medicine, Baghdad university, Iraq.
wafa R. AL-Omari Dept. of obstetric & Gynecology, college of medicine, Baghdad university, Iraq.
warkaa mahmood ali Department of histopathology, college of Dentistry, Baghdad university, Iraq.

DOI:

https://doi.org/10.32007/jfacmedbagdad.4721650

Keywords:

PET: preeclampsia, IgG: immunoglobuline. BP: blood pressure.

Abstract

Summary
Background: The role of humoral immunity in the pathogenesis of PET is well known so that an altered immune response could be the cause of this disease . Objectives: to evaluate the rule ofplacenta _ bound IgG in the pathogenesis of PET. Methods: 31 pregnant women were included in this study delivered by cesarean section at Baghdad Teaching Hospital , 16 of them were diagnosed and treated for PET. while the rest 15 cases were of normal women of using direct immunoflorescnt test, the level of IgG was detected.
Result: Tthe study showed a significant higher level of IgG in the placental biopsy of PET cases than those of control group using ttest, (P<0.025),
Conclusion: Trophoblastic bound IgG plays an important role in the pathogenesis of PET as a part of altered humoral immune response against placental tissue in those patients.