Relationship of Pruritus with Biochemical and Haematological Parameters in Haemodialysis Patients (A Single Center Study).

Authors

  • Ban Ghassan College of Science, University of Baghdad.
  • Jaffar N. Jaffar Alalsaidissa College of Medicine, University of Baghdad.
  • Ali J. Hashim Al-Saedi Nephrologyand Transplant Center.
  • Sabah N. Alawchi Dept. of Biology, College of Science, University of Baghdad.

DOI:

https://doi.org/10.32007/jfacmedbagdad.574396

Keywords:

pruritus, haemodialysis, biochemical and haematological parameters.

Abstract

Background: Pruritus often constitutes a major problem for patients with end stage renal disease. The pathophysiological mechanism of chronic kidney disease -associated pruritus is poorly defined.
Objectives: To evaluate the prevalence of uremic pruritus in dialysis patients and their correlation with the laboratory and clinical parameters in some Iraqi patients with chronic renal disease.
Patients & methods: This analytic, descriptive, cross-sectional study was performed on 103 patients on haemodialysis. Blood urea, creatinine, calcium, phosphorus, alkaline phosphatase and parathyroid hormone were determined. Complete blood count was also performed.
Results: Of the 103 patients included in the study the, 79 patients (76.7%) had pruritus of whom, 27 (34.1%) had mild pruritus, 30 (38%) had moderate and 22 (27.9%) had severe pruritus. No significant association (p> 0.05) was found between pruritus and each of age and haemodialysis duration. There was no significant difference (p > 0.05) in the urea, creatinine, calcium, phosphorus, alkaline phosphatase, parathyroid hormone, hemoglobin, hematocrit, white blood cells, neutrophils, eoisinophils, basophils mean values among patients who had no pruritus, mild, moderate and severe pruritus. A significant positive correlation (p > 0.05) was found between severity of pruritus in pruritic patients and each of age, hemoglobin and hematocrit levels.
Conclusion: Our study showed that age, hemoglobin and hematocrit levels had a significant positive correlation with the severity of pruritus in pruritic patients.

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Published

03.01.2016

How to Cite

1.
Ghassan B, Jaffar Alalsaidissa JN, Hashim Al-Saedi AJ, Alawchi SN. Relationship of Pruritus with Biochemical and Haematological Parameters in Haemodialysis Patients (A Single Center Study). J Fac Med Baghdad [Internet]. 2016 Jan. 3 [cited 2024 Dec. 26];57(4):306-11. Available from: https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/396

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