Relationship of Pruritus with Biochemical and Haematological Parameters in Haemodialysis Patients (A Single Center Study).
Background: Pruritus often constitutes a major problem for patients with end stage renal disease. The pathophysiological mechanism of chronic kidney disease -associated pruritus is poorly defined.
Objectives: To evaluate the prevalence of uremic pruritus in dialysis patients and their correlation with the laboratory and clinical parameters in some Iraqi patients with chronic renal disease.
Patients & methods: This analytic, descriptive, cross-sectional study was performed on 103 patients on haemodialysis. Blood urea, creatinine, calcium, phosphorus, alkaline phosphatase and parathyroid hormone were determined. Complete blood count was also performed.
Results: Of the 103 patients included in the study the, 79 patients (76.7%) had pruritus of whom, 27 (34.1%) had mild pruritus, 30 (38%) had moderate and 22 (27.9%) had severe pruritus. No significant association (p> 0.05) was found between pruritus and each of age and haemodialysis duration. There was no significant difference (p > 0.05) in the urea, creatinine, calcium, phosphorus, alkaline phosphatase, parathyroid hormone, hemoglobin, hematocrit, white blood cells, neutrophils, eoisinophils, basophils mean values among patients who had no pruritus, mild, moderate and severe pruritus. A significant positive correlation (p > 0.05) was found between severity of pruritus in pruritic patients and each of age, hemoglobin and hematocrit levels.
Conclusion: Our study showed that age, hemoglobin and hematocrit levels had a significant positive correlation with the severity of pruritus in pruritic patients.
For all articles published in Journal of the Faculty of Medicine Baghdad, copyright is retained by the authors. Articles are licensed under an open access Creative Commons CC BY NC 4.0 license, meaning that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited. These conditions allow for maximum use and exposure of the work, while ensuring that the authors receive proper rights.