Neoadjuvant Chemotherapy in Nasopharyngeal Carcinoma

Authors

  • Khudair J. Sabeeh Al-Rawaq Dept of surgery, College of Medicine / University of Baghdad

DOI:

https://doi.org/10.32007/jfacmedbagdad.541761

Keywords:

Nasopharyngeal Carcinoma, radiotherapy, neoadjuvant chemotherapy, concomitant chemoradiation.

Abstract

Back ground: nasopharyngeal carcinoma is rare in Iraq and the treatment of this tumor is usually by radiotherapy and chemotherapy.
Objectives: this study was conducted to estimate the effect of neoadjuvant chemotherapy in Iraqi patients with nasopharyngeal carcinoma
Patients and methods: This study included sixty patients already diagnosed with nasopharyngeal tumors who attended the department of oncology in Baghdad teaching hospital during the period from January 2009 to December 2010,50 patients of them were treated by using combination chemotherapy in the form of Paclitaxel,5Flurouracil and cisplatinol for 4 courses prior to radiotherapy. Neoadjuvant chemotherapy was given due to advanced stage at presentation and due to long waiting list for radiotherapy which takes at least 6 months.10 patients were excluded from the study due to different reasons.
Results: About half of the patients had partial response to neoadjuvant chemotherapy,only 8 patients (16%) had complete response, 12 patients (24%) did not show any response and 5 patients (10%) have progressive disease during the course of neo adjuvant chemotherapy.
Conclusion: Neoadjuvant chemotherapy is beneficial in the management of Nasopharyngeal Cancer regarding local control and overall response rate.

Downloads

Download data is not yet available.

Downloads

Published

2012-04-01

How to Cite

1.
Neoadjuvant Chemotherapy in Nasopharyngeal Carcinoma. JFacMedBagdad [Internet]. 2012 Apr. 1 [cited 2024 Mar. 29];54(1):7-9. Available from: https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/761

Similar Articles

1-10 of 125

You may also start an advanced similarity search for this article.