Antiphospholipid antibodies in forty young patients with stroke

Khudhair A. AL- Khalissi; Mohamed S. Abass; Ali A. Nabat

doi:10.32007/jfacmedbagdad.572342

Authors

Khudhair A. AL- Khalissi College of medicine – Baghdad University. Deparment. of medicine and Hematology.
Mohamed S. Abass Baghdad Teaching Hospital. Specialist in Hematology.
Ali A. Nabat Baghdad Teaching Hospital negative (7).

DOI:

https://doi.org/10.32007/jfacmedbagdad.572342

Keywords:

Stroke, Antiphospholipid Syndrome, Antiphospholipid Antibodies.

Abstract

Background: Cerebral ischemia associated with Antiphospholipid Syndrome(APS) is a common arterial manifestation in adults.
Objectives: To look for the frequency of Antiphospholipid Antibodies (aPL), and their relation with other risk factors in young patients with cerebral ischemia.
Patients and methods: A retrospective study of 40 young patient’s ≤ 50 years with stroke collected from medical and neurological wards of Baghdad Teaching Hospital (BTH) from January - December 2009. All were inquired about the presence of risk factors of stroke, and sent for aPL including Anticardiolipin (ACL) and Lupus Anticoagulant (LA).
Results: Eight (20%) had ACL. Nine (22.5%) had LA. Both were present in 6(15%). ACL and/or LA were present in 11 (27.5%). Thirty three (82.5) patients had at least one risk factor, 8 of them had aPL, while 7(17.5%) had no risk factor and only 3 of them had aPL (p 0.1806).
Conclusion: Antiphospholipid Syndrome is a possible risk factor of stroke and any young patient with stroke should be screened for aPL .