Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia.

  • Abdul Sattar A. Khammas Dept. of Radiological Techniques, College of Medical and Health Technology/ Baghdad, University of Middle Technical
  • Safwan S. Mohammed Dept. of Imaging, Faculty of Medicine and Health Sciences, University of Putra Malaysia
  • Hasyma Abu Hassan Dept. of Imaging, Faculty of Medicine and Health Sciences, University of Putra Malaysia.
  • Hayati k. Shahar Dept. of Public Health, Faculty of Medicine and Health Sciences, University of Putra Malaysia.
  • Ramlah M. Ibrahim Dept. of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, University of Putra Malaysia
  • Nurul N. Mohamad Nasir Dept. of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, University of Putra Malaysia
  • Sarah Q. M. Salih Computer Center, College of Medical and Health Technology/ Baghdad, University of Middle Technical
  • Rozi Mahmud Cancer Resource and Education Centre (CaRE), Faculty of Medicine and Health Sciences, University of Putra Malaysia
Keywords: Non-alcoholic fatty liver disease, NAFLD grades, sonography, urban population

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is a very common liver disease in the world, particularly in Western and developed countries. It is rapidly growing in the Asia- Pacific region.
Objectives: This study was designed to determine the association between risk factors and non-alcoholic fatty liver disease grades among Malaysian adults.
Patients and Methods: A cross-sectional observational study design was prospectively carried out in this study. Consecutive 628 respondents who attended for a medical checkup at urban health center had been recruited for the study. All respondents had the physical examination, blood tests, clinical assessments, and abdominal ultrasound. A structured self-administered questionnaire has been also used in this study in this survey.
Results: From a total of 628 “health screened” subjects, 235 subjects (37.4%) were diagnosed to have non-alcoholic fatty liver disease. Female gender and Chinese race were predominant in our study population. Of those with NAFLD, more than half subjects (63.4) had a moderate grade of non-alcoholic fatty liver disease. The mean age of the study population was 54.54 ±6.69 years. Differences of the mean body mass index (BMI) and waist to hip ratio (WHR) were found to be significant among non-alcoholic fatty liver disease grades (P< 0.001). Similarly, mean triglycerides (TG) and high-densiy lipoprotein-cholesterol (HDL-C) levels had significant differences among non-alcoholic fatty liver disease grades (P< 0.001 and P= 0.016, respectively).
Conclusion: the non-alcoholic fatty liver disease is common among urban Malaysian adult population. Anthropometric measurements were closely correlated with non-alcoholic fatty liver disease grades.
Keywords: Non-alcoholic fatty liver disease, NAFLD grades, sonography, urban population.

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Published
2018-04-01
How to Cite
1.
Khammas AS, Mohammed S, Hassan H, Shahar H, Ibrahim R, Mohamad Nasir N, M. Salih S, Mahmud R. Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia. J Fac Med Bagdad [Internet]. 1Apr.2018 [cited 24Jan.2020];60(1):32-7. Available from: http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/37