Seasonal variations of childhood Guillain-Barre Syndrome in South west Iran

  • Ali A. Momen Dept. of Pediatric, College of Medicine, Golestan hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
  • Abdolhussein Shakurnia Dept. of Immunology, College of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
  • Mahsa Sarrami Medical student, College of Medicine, University of Newcastle, Australia
Keywords: Guillain-Barre syndrome, seasonal variation, children, South-West Iran

Abstract

Background: It was found that the occurrence of Guillain-Barre Syndrome (GBS) varies in respect to
the month and season; this variation has not been adequately studied.
Objective: To determine the month and seasonal variation of GBS in children in the Khuzestan
province, south west Iran, during a 10-year period (2006-2015).
Patients and methods: We extracted data retrospectively from acute flaccid paralysis committee
from healthcare centers in all cities of the province, over a 10-year period (from January 1, 2006 to
December 31, 2015). In this study all children under 15 years of age with Guillain-Barre syndrome
were surveyed. In order to compare the frequency of GBS in different seasons and months we used the
Chi Square test.
Results: From 187 cases of GBS, 101 (54%) were males, 86 (46%) females with sex ratio 1.17:1. The
mean age of the children was 5.39 ± 4.02 years. The highest occurrence of GBS was observed in
autumn (32.1%) followed by winter (27.3%). The highest number of cases (28; 15%) occurred in
December and the lowest (8; 4.3%) in September. There was seasonal (P=0.006) and monthly
(P=0.036) variation in occurrence of GBS throughout the year with more prevalence in autumn ,
September and December.
Conclusion: Our study showed that there is a significant monthly and seasonal variation in children
with GBS in Khuzestan province.

Downloads

Download data is not yet available.
Published
2018-09-02
How to Cite
1.
Momen A, Shakurnia A, Sarrami M. Seasonal variations of childhood Guillain-Barre Syndrome in South west Iran. J Fac Med Bagdad [Internet]. 2Sep.2018 [cited 24Jan.2020];60(2):108-12. Available from: http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/16