The possible association between Chlamydia pneumoniae infection and asthma.

Mahmood Sh. Al-Zaidi; Haider S. Kadhim; Haider Ahmed Shemran

doi:10.32007/jfacmedbagdad.523984

Authors

Mahmood Sh. Al-Zaidi Dept. of Medical Microbiology, College of Medicine, Al-Nahrain University.
Haider S. Kadhim Dept. of Medical Microbiology, College of Medicine, Al-Nahrain University.
Haider Ahmed Shemran Dept. of Medical Microbiology, College of Medicine, Al-Nahrain University.

DOI:

https://doi.org/10.32007/jfacmedbagdad.523984

Keywords:

Chlamydia pneumoniae, Asthma, Chest infection

Abstract

Background: Many etiological factors have been implicated in the pathogenesis of Asthma like; viruses, bacteria and Chlamydia pneumoniae. This study focuses on the role of Chlamydia
pneumoniae in asthma pathogenesis.
Patients and Methods: The detection of Anti-Chlamydia pneumoniae antibodies IgA, IgM and IgG in patients by ELISA, for 35 patients, 18 asthmatic patients, 12 patients with chest infection with no history of asthma, and 5 apparently healthy as control subjects.
Results: The results showed that 80% and 70% of the patients were negative for anti- Chlamydia pneumonia antibodies IgA and IgM respectively, while significantly (p<0.05) high number (73%) of patients were positive for IgG, of which significant number (p<0.05) of them, 63% were asthmatic and 36% were non-asthmatic chest infection.
Conclusion: this study may support the association between Chlamydia pneumoniae and asthma.