Cadmium Chloride (CdCl2)-Induced Apoptosis in Liver of Mice

Authors

  • Khalid Hamdan Gathwan College of Dentistry, dept. of basic science.

DOI:

https://doi.org/10.32007/jfacmedbagdad.4831507

Keywords:

Cadmium, mice, metal analysis, apoptosis.

Abstract

Background: Cadmium (Cd) is an industrial and environmental pollutant that affect adversely a number of organs in humans and other mammals.
Objectives: To study the effect of cadmium on liver of mice.
Material and Methods: Male Balb/c mice weighing 30-32 gm, 60 days old, were treated intraperitoneally (ip) with (1-10mg/kg body wt. /CdCl2). The body weight, liver weight, histological examination of liver, SEM, metal analysis along with DNA ladder for apoptosis.
Results: Cadmium induced both a time, and dose dependent increase in apoptotic, severity of necrosis. Liver weight, body weight decreased with increase of dose, while metal content was increased by increase of dose.
Conclusion: It has been concluded that cadmium caused necrotic effect on liver and apoptotic as well as decreased body weight and liver weight.

Downloads

Download data is not yet available.

Downloads

Published

2006-10-01

How to Cite

1.
Cadmium Chloride (CdCl2)-Induced Apoptosis in Liver of Mice. JFacMedBagdad [Internet]. 2006 Oct. 1 [cited 2024 Mar. 29];48(3):309-12. Available from: https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1507

Similar Articles

1-10 of 178

You may also start an advanced similarity search for this article.