CD-Markers as an immunological aspect in patients with visceral leishmaniasis

Jabbar R. Zangor Al-Autabbi; Zainab A. Hamed. Al-Rubayee

doi:10.32007/jfacmedbagdad.5141096

Authors

Jabbar R. Zangor Al-Autabbi Department of Microbiology /College of Medicine /Baghdad University
Zainab A. Hamed. Al-Rubayee Department of Microbiology /College of Medicine /Baghdad University

DOI:

https://doi.org/10.32007/jfacmedbagdad.5141096

Keywords:

CD-Markers profile, leishmania donovani, amastigote form

Abstract

Back ground: Visceral leishmaniasis is an endemic protozoan disease in Iraq. Recovery from this disease confers a solid and permanent immunity. Immunological assessment of our patients was carried out and the results showed a significant reduction in the percentage of CD3, CD56 and a significant increase in the percentage of CD19 in the peripheral blood lymphocyte of VL in comparison with control group.
Patients and methods: Indirect immunofluorescence technique analysis was performed to detect the percentage of CD3, CD19and CD56 positive lymphocytes.
Results: Our results in the patients groups showed decrease in the percentage of CD3, CD56 and increase in the percentage of CD19. Follow up of patients after treatment showed a significant increase in the percentage of CD3, CD56, but they were still lower than their normal range .
Conclusion:- CD3,CD56, were decreased in VL infection then increased after treatment but it was less than its normal range, while CD19 was increased in VL when compared with control group.