The role of serum IL-6 changes in evaluation of endometriosis

  • Tharwa H. Hassan AL-Tai Dept. of Microbiology,College of Medicine,University of Baghdad.
  • Hayfaa S. AL-Hadithi Dept. of Microbiology ,College of Medicine,University of Baghdad.
  • Hind S. Abdulsalam Dept. of Gynecology,College of Medicine,University of Baghdad.
DOI: https://doi.org/10.32007/jfacmedbagdad.v2158-161%25
Keywords: Endometriosis, IL-6.

Abstract

Background:- Endometriosis is a common chronic gynecological disorder characterized by the presence and proliferation of functional endometrial gland and stroma outside the uterine cavity, affecting approximately 10% of reproductive age women. Il-6 level increased in the patient with endometriosis.
Objective:- Evaluate the correlation of IL-6 levels with the degree of severity of endometriosis
Patients and methods:- In this study, 84 samples 51women with endometriosis (20 newly diagnosed and 31 treated cases) and 33 of healthy control group, were collected starting from November 2011 to end of January 2012, to investigate the IL-6 serum level by using ELISA kit.
Results :- Endometriosis patients mainly presented at the age between (28-37). IL-6 serum levels were significantly decrease in those with stage IV endometriosis. Also appear to be significantly affected by the use of danazol or zoladex treatment of endometriosis and remain low even in treated patients. Serum IL-6 test was highly specific but with low sensitivity.
Conclusion:-Serum IL-6 concentration seem to be the highly specific test that can be used as an early detection marker for endometriosis.

Downloads

Download data is not yet available.
Published
2013-07-01
How to Cite
1.
Hassan AL-Tai T, AL-Hadithi H, Abdulsalam H. The role of serum IL-6 changes in evaluation of endometriosis. J Fac Med Bagdad [Internet]. 1Jul.2013 [cited 30Nov.2019];55(2):158-61. Available from: http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/646
Issue
Vol 55 No 2 (2013): Journal of the Faculty of Medicine Baghdad
Section
Articles

 For all articles published in Journal of the Faculty of Medicine Baghdad, copyright is retained by the authors. Articles are licensed under an open access Creative Commons CC BY NC 4.0 license, meaning that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited. These conditions allow for maximum use and exposure of the work, while ensuring that the authors receive proper rights.