Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients

  • Yacoob Y. Al-Rubayei Medical Laboratory Science Technology / College of Medical & Health Technology.
  • Batool A. Al-Haidary Clinical Immunology / Assist. Prof. / College of Medical & Health Technology.
  • Wala'a E. Jasim Biochemistry / Assist. Prof./ College of Medical & Health Technology.
Keywords: Asthma, IL-5, ELISA, BMI.

Abstract

Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5).

The  aim of this study to demonstrate the association between IL-5 and obesity in asthma development. 
Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI).
Results: This study revealed a significant correlation between IL-5 concentration and BMI (P<0.05), particularly among females.
Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5.

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Published
2007-04-01
How to Cite
1.
Al-Rubayei Y, Al-Haidary B, Jasim W. Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients. J Fac Med Bagdad [Internet]. 1Apr.2007 [cited 29Nov.2019];49(1):116-20. Available from: http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1430